Pharmaceutical Chemistry Novel Aspects
Pharmaceutical chemistry is a subdivision at the intersection of chemistry, especially synthetic organic chemistry, and pharmacology and various biological specialties, where they are involved with drug design, chemical synthesis and development for a market, or bio-active molecules (drugs). In particular, Pharmaceutical chemistry in its most common guide focusing on small organic molecules/entities encompasses synthetic organic chemistry and aspects of natural products chemistry and computational chemistry in close combination with chemical biology, enzymology, and structural biology, together targeting at the drug discovery and development of new different therapeutic agents. It involves chemical aspects of identification, and later systematic, thorough synthetic alteration of new chemical entities to make them appropriate for therapeutic use. It includes synthetic and computational aspects of the study of existing drugs and agents in development in relation to their bioactivities (biological activities and properties), i.e., understanding their structure-activity relationships (SAR). Pharmaceutical chemistry is focused on quality aspects of medicines and aims to assure fitness for purpose of medicinal products.